Gluta Universe Life Sciences

Thymosin Beta-4 is a naturally occurring peptide present in almost all animal and human cells.  TB500 is a synthetic peptide that has been directly linked to recovery as it is plays a vital role in building new blood vessels, new small muscle tissue fibers, cell migration and blood cell reproduction. 

TB500 is a preparation that is obtained synthetically and is a complete analog of a natural peptide Thymosin beta 4, which is produced by the human body. This substance has been used in medicine for a long time, in order to accelerate the healing and recovery process.

TB500 consists of 44 amino acids and has a unique ability to neutralize the effects of stress quickly and restore the body at the cellular level. A powerful reparative effects of the peptide cause a sharp burst of vital activity in all body organs and systems without causing addiction or rejection. It is recommended for athletes, bodybuilders and people recovering from injuries or cardiovascular diseases to buy TB-500 and take it regularly.

DES IGF-1 is the shorter version of the IGF-1 chain. It is five (5) times more powerful than IGF-LR3 and ten (10) times more powerful than regular base IGF-1. The half-life for DES is about 20-30 minutes, which means this is a very delicate chain. Therefore, administration should only be done at the site where you want to see muscle growth. DES has the ability to stimulate muscle hyperplasia better than LR3. In simple terms, it’s best used for site injections, rather than overall growth.

In addition, DES is known to bind to receptors that have been deformed by lactic acid, which is often present during workouts. This allows the DES to attach itself to a mutated receptor and signal tissue growth during training. DES can be used longer and more frequently than LR3. It has been rumored that the first official use of IGF-1 as a performance enhancing drug was in the early 1990s by then-Mr. Olympia Dorian Yates, which at the time was considered an extremely rare and expensive drug to obtain, after which its use quickly spread amongst the bodybuilding community.

IGF-1 DES (reported as des(1-3)IGF-I in scientific studies) is a truncated version of naturally occurring IGF-1. The 70 amino acid form of activated IGF-1 is essential for normal human growth and development and acts via IGF-1 receptors to exert an anabolic effect to build muscle, which is why IGF-1 is important in bodybuilding [1]. Low IGF-1 levels are linked to poor growth and a number of metabolic disorders [2]. Multiple tissues inside the body produce IGF-1 and its site of synthesis affects its function. The majority of IGF-1 is made by the liver and is transported to other tissues in the bloodstream, where it acts as an endocrine hormone [3]. Importantly, IGF-1 is a central growth hormone that controls the anabolic growth promoting effect of growth hormone. It also has a growth hormone independent growth-stimulating effect, which is optimised when combined with growth hormone [4]. IGF-1 DES has been specially formulated to lack three amino acids from the end of natural IGF-1, which increases its potency to around ten-fold higher when compared to regular IGF-1 [5]. This increase in potency is due to the fact that IGF-1 DES does not bind to IGF-binding proteins like IGF-1 [6]. Usually, IGF-binding proteins immediately block the growth-promoting activities of IGF-1, but they are unable to bind and block IGF-1 DES. This means that the peptide is free to promote muscle and bone growth and repair and smooth muscle survival [7, 8]. IGF-I DES has been shown to stimulate body growth in a range of tissues in multiple animal studies [9]. Animal studies have also shown that carcass fat was reduced alongside muscle gains [9]. In diabetic animals the modified peptide demonstrated effects throughout the alimentary tract and led to improvements in nutrient uptake [10]. Although no human clinical trials using IGF-1 DES have been carried out, studies have uncovered that the peptide is naturally found in the human brain and brain cell studies have shown that it can protect against brain damage and that it promotes brain growth .

DES IGF-1 is the shorter version of the IGF-1 chain. It is five (5) times more powerful than IGF-LR3 and ten (10) times more powerful than regular base IGF-1. The half-life for DES is about 20-30 minutes, which means this is a very delicate chain. Therefore, administration should only be done at the site where you want to see muscle growth. DES has the ability to stimulate muscle hyperplasia better than LR3. In simple terms, it’s best used for site injections, rather than overall growth.

In addition, DES is known to bind to receptors that have been deformed by lactic acid, which is often present during workouts. This allows the DES to attach itself to a mutated receptor and signal tissue growth during training. DES can be used longer and more frequently than LR3. It has been rumored that the first official use of IGF-1 as a performance enhancing drug was in the early 1990s by then-Mr. Olympia Dorian Yates, which at the time was considered an extremely rare and expensive drug to obtain, after which its use quickly spread amongst the bodybuilding community.

IGF-1 DES (reported as des(1-3)IGF-I in scientific studies) is a truncated version of naturally occurring IGF-1. The 70 amino acid form of activated IGF-1 is essential for normal human growth and development and acts via IGF-1 receptors to exert an anabolic effect to build muscle, which is why IGF-1 is important in bodybuilding [1]. Low IGF-1 levels are linked to poor growth and a number of metabolic disorders [2]. Multiple tissues inside the body produce IGF-1 and its site of synthesis affects its function. The majority of IGF-1 is made by the liver and is transported to other tissues in the bloodstream, where it acts as an endocrine hormone [3]. Importantly, IGF-1 is a central growth hormone that controls the anabolic growth promoting effect of growth hormone. It also has a growth hormone independent growth-stimulating effect, which is optimised when combined with growth hormone [4]. IGF-1 DES has been specially formulated to lack three amino acids from the end of natural IGF-1, which increases its potency to around ten-fold higher when compared to regular IGF-1 [5]. This increase in potency is due to the fact that IGF-1 DES does not bind to IGF-binding proteins like IGF-1 [6]. Usually, IGF-binding proteins immediately block the growth-promoting activities of IGF-1, but they are unable to bind and block IGF-1 DES. This means that the peptide is free to promote muscle and bone growth and repair and smooth muscle survival [7, 8]. IGF-I DES has been shown to stimulate body growth in a range of tissues in multiple animal studies [9]. Animal studies have also shown that carcass fat was reduced alongside muscle gains [9]. In diabetic animals the modified peptide demonstrated effects throughout the alimentary tract and led to improvements in nutrient uptake [10]. Although no human clinical trials using IGF-1 DES have been carried out, studies have uncovered that the peptide is naturally found in the human brain and brain cell studies have shown that it can protect against brain damage and that it promotes brain growth .